What is the Endocannabinoid System?


First discovered in the 1990’s the endocannabinoids in the human body. These cannabis identical substances are naturally produced by the human body. Scientists studied the cannabinoids vigorously and concluded that the effects of cannabis are a product of the cannabinoids mimicking our endocannabinoids. The main function of the endocannabinoid system is to maintain bodily homeostasis. It is the body’s way to create balance and harmony during environmental changes. This newly discovered system has taxonomic evidence that it has evolved over a 500-million-year span. Biologist have found the endocannabinoid system to be present in all vertebrates which include amphibians, birds, fish, and mammals.

Initially it was thought that endocannabinoid receptors were only present in the brain and in nerves. Though more thorough research it was discovered that the receptors are present throughout the body. Our skin, immune cells, bone, fat tissue, liver, pancreas, skeletal muscle, heart, blood vessels, kidney, and gastrointestinal tract all have cannabinoids to help regulate their respective systems. This wide range of influence means that the endocannabinoid system is involved in a wide variety of processes, including pain, memory, mood, appetite, stress, sleep, metabolism, immune function, and reproductive function. Endocannabinoids are arguably one of the most widespread and versatile signaling molecules known to man.

What is the role of the Endocannabinoid System?

The endocannabinoid system is an important in the function of brain, endocrine, and immune tissues. It has strong evidence that it plays an especially important regulatory role of hormones relating to reproductive functions and stress response. In humans this system also balances energy and influences the function of the food intake centers of the central nervous system and gastrointestinal tract activity. Rimonabant, a cannabinoid-1 receptor (CB1) blocker, has been shown to reduce body weight and improve an individual’s cardiovascular risk factor in the obese by increasing HDL-cholesterol and adiponectin blood levels as well as decreasing LDL-cholesterol, leptin, and C-reactive protein concentrations.

Cannabinoid Therapy

Cannabinoids have demonstrated the potential for a wide spectrum of therapeutic uses. Synthetic THC brands are FDA approved for chemotherapy-induced nausea and vomiting. The appetite and weight loss related to HIV/AIDS may also be relieved by THC. Brands with a combination of THC and CBD are approved in 30 countries outside of the U.S. for muscle spasticity in Multiple Sclerosis. CBD is FDA approved to treat certain pediatric seizure disorders and may reduce seizures in some children with epilepsy disorders.

Cannabinoids have a range of effects that may be therapeutically useful, including antioxidant, neuroprotective, anti-inflammatory, anti-pain, anti-tumor, anti-psychotic, anti-anxiety, and sleep modulating effects.

The U.S. National Academy of Sciences, Engineering and Medicine concluded there was “substantial evidence” cannabinoids were effective for Chronic Pain, Chemotherapy induced Nausea and Vomiting, and Spasticity from Multiple Sclerosis. In addition, they had concluded there was “moderate evidence” cannabinoids were effective for improving sleep quality in people suffering from chronic pain, sleep apnea, and fibromyalgia. Other areas demonstrating promise but where current evidence is more” limited” include Post Traumatic Stress disorder (PTSD), Tourette’s syndrome, social anxiety, and traumatic brain injury.

How to fuel the endocannabinoid system

To supply the ECS you need supply it with cannabinoids. Steve’s Goods has a variety of CBD products. Many products include CBG, the mother of all cannabinoids. To get a variety of cannabinoids look for our full spectrum products such as our CBG oil. Each CBG batch is lab tested and the results are posted with the product image. Hear are a few of our favorite products.

    • This is a versatile form of CBD Oil. CBD is soluble in high proof alcohol. A tincture is simply a CBD infused alcohol. They go directly on your tongue, under your tongue, in your food, or in you drinks. Tinctures have a longer shelf life, are more bio-accessible, and taste better. Try flavors like Blueberry and Watermelon. They are delicious!
    • A pure and potent form of CBD. They can take forms such as wax and shatter that can be dabbed on its own or sprinkled over your favorite smoking blend.
    • Try a tasty treat such as gummies, lollipops, or coffee with boosted benefits. Get an endorphin rush from pleasurable snacks while also reducing your anxiety via CBD.
    • Focus pain relief quickly Creams and Bath Bombs. They will make you feel better and provide nourishment for your skin. A popular item is the Steve’s Goods Wowzer On a Stick. Simply apply it on an area that is inflamed or stiff and relief will be nearly immediate.
  • CBG
    • Cannabigerol is the “Mother of all cannabinoids.” Through photosynthesis it breaks down into chemicals like CBD and THC. This makes it exceedingly difficult to produce it naturally. We spent over a year of specialized research to perfect our all natural CBG.
    • This fine white powder is 99% pure CBD! It is created by refining down Hemp oil. It can be added to your cookies, coffee, tea, or smoking blend.

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